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Discover Supplement-Drug Interactions
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Last Updated: 2 months ago
drug:
Megestrol Acetate
supplement:
Adrenocorticotropic Hormone
Research Papers that Mention the Interaction
“ResultsCompared to placebo, acute administration of megestrol resulted in a significant decrease in morning ACTH and cortisol levels.”
“The suppression of ACTH after pretreatment with megestrol was less pronounced than after pretreatment with hydrocortisone.”
Acute effects of megestrol on the hypothalamic–pituitary–adrenal axis“Baseline ACTH and cortisol levels, as well as ACTH and cortisol levels after administration of CCK-4, were significantly reduced after pretreatment with megestrol.”
“Administration of megestrol acetate also produced a progressive decrease in both resting plasma cortisol concentrations and cortisol concentrations after ACTH stimulation.”
Effects of megestrol acetate on glucose tolerance and growth hormone secretion in the cat.“ Megestrol acetate inhibited both the release and total ACTH content of the anterior pituitary gland, while RU 38486 increased both the release and the total ACTH content.”
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