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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Mecamylamine and Huperzine A

supplement:

Huperzine A

Research Papers that Mention the Interaction

5) HupA inhibition of T-cell proliferation is reversed by the nicotinic acetylcholinergic receptor antagonist mecamylamine.
Experimental Neurology  •  2012  |  View Paper
Mecamylamine , a nicotinic acetylcholine receptor (nAChR) antagonist, totally abolished the inhibitory effects of huperzine A on ischemia‐induced glial cells activation.
…,mecamylamine partially reversed the infarct …‐reducing effects of huperzine A. In conclusion, our results demonstrate that huperzine A exhibits neuroprotective effects against transient focal cerebral ischemia‐induced brain injury and suggest that the protection mechanism may involve a cholinergic anti‐inflammatory pathway, in which nAChR plays an essential role.
Journal of neurochemistry  •  2008  |  View Paper