Possible Interaction: Mazindol and Vitamin C

“This effect of ascorbic acid on the efflux of [3H]MPP+ was attenuated by mazindol , a blocker of dopamine uptake.”

“The differences observed in the alteration of dopaminergic transport and mazindol binding by ascorbic acid suggest that ascorbic acid's effects on [3H] MPP+ transport are related to translocation and/or dissociation processes occurring subsequent to the initial binding event.”

“Supplementary vitamin C reduced the anti-obesity actions of fenfluramine, Mazindol and Diethylpropion.”