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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Marijuana
drug:
Theophylline
Research Papers that Mention the Interaction
“Smoked cannabis herb (marijuana) likely induces CYP1A2 mediated theophylline metabolism, although the role of cannabinoids specifically in eliciting this effect is questionable.”
Exogenous cannabinoids as substrates, inhibitors, and inducers of human drug metabolizing enzymes: a systematic review“Studies with theophylline have demonstrated that both tobacco and marijuana markedly alter its clearance in man.”
“ Theophylline clearance is markedly increased by tobacco or marihuana smoke.”
“Data, which are not very conclusive, indicate that heavy marijuana use may have an inhibitory effect on metabolism of some drugs and an inducing effect on others such as theophylline.”
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