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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Marijuana and Pentobarbital



Research Papers that Mention the Interaction

All but one of the cannabis fractions prolonged the pentobarbital sleeping-time and disrupted the nest-building activity of mice in a way not related to their content in the main cannabinoids.
Experientia  •  2005  |  View Paper
The sleeping time of dogs that smoked marihuana and were then injected with sodium pentobarbital increased in proportion to the number of cigarettes smoked.
Toxicology and applied pharmacology  •  1978  |  View Paper
7 It is concluded that cannabis may affect pentobarbitone and ether anaesthesia in mice at least partially by a direct depressant effect, and that the cannabis‐induced prolongation of anaesthesia is probably unrelated to any effect on central 5‐hydroxytryptamine or catecholamine neurones.
British journal of pharmacology  •  1974  |  View Paper