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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Marijuana
drug:
Pentobarbital
Research Papers that Mention the Interaction
“All but one of the cannabis fractions prolonged the pentobarbital sleeping-time and disrupted the nest-building activity of mice in a way not related to their content in the main cannabinoids.”
The pharmacological effect of fractions obtained by smoking cannabis through a water-pipe. II. A second fractionation step“The sleeping time of dogs that smoked marihuana and were then injected with sodium pentobarbital increased in proportion to the number of cigarettes smoked.”
“7 It is concluded that cannabis may affect pentobarbitone and ether anaesthesia in mice at least partially by a direct depressant effect, and that the cannabis‐induced prolongation of anaesthesia is probably unrelated to any effect on central 5‐hydroxytryptamine or catecholamine neurones.”
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