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Last Updated: 3 years ago

Possible Interaction: Marijuana and Oxycodone

supplement:

Marijuana

Research Papers that Mention the Interaction

Although active cannabis and 2.5 mg oxycodone alone failed to elicit analgesia, combined they increased pain threshold and tolerance (p ≤ 0.05).
Cannabis enhances the analgesic effects of sub-threshold oxycodone , suggesting synergy, without increases in cannabis’s abuse liability.
This double-blind, placebo-controlled, within-subject study determined if cannabis enhances the analgesic effects of low dose oxycodone using a validated experimental model of pain and its effects on abuse liability.
Neuropsychopharmacology  •  2018  |  View Paper