“Although active cannabis and 2.5 mg oxycodone alone failed to elicit analgesia, combined they increased pain threshold and tolerance (p ≤ 0.05).”
“ Cannabis enhances the analgesic effects of sub-threshold oxycodone , suggesting synergy, without increases in cannabis’s abuse liability.”
“This double-blind, placebo-controlled, within-subject study determined if cannabis enhances the analgesic effects of low dose oxycodone using a validated experimental model of pain and its effects on abuse liability.”