supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
supplement:
Marijuana
drug:
Gabapentin
Research Papers that Mention the Interaction
“Relative to placebo, gabapentin significantly reduced cannabis use as measured both by urine toxicology (p=0.001) and by the Timeline Followback Interview (p=0.004), and significantly decreased withdrawal symptoms as measured by the Marijuana Withdrawal Checklist (p<0.001).”
A Proof-of-Concept Randomized Controlled Study of Gabapentin: Effects on Cannabis Use, Withdrawal and Executive Function Deficits in Cannabis-Dependent Adults“Participants reporting gabapentin misuse had higher odds of reporting (mis)use of marijuana , cocaine, methamphetamine, prescription opioids, benzodiazepines, prescription stimulants, fentanyl, and buprenorphine (p < .042); severe substance use disorder (p < .000); and recent physical pain (p < .003).”
“No medications are approved for cannabis use disorder (CUD), though a small clinical trial demonstrated that the voltage-dependent calcium channel (VDCC) ligand gabapentin reduced cannabis use in treatment seekers.”
Influence of pregabalin maintenance on cannabis effects and related behaviors in daily cannabis users.“Some drugs, such as CB1 agonists, gabapentin , and N-acetylcysteine, have been shown to produce improvements in some symptoms of CUD in single studies, but these have not been replicated.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback