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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Mannose
drug:
Tiazofurin
Research Papers that Mention the Interaction
“Inhibition of fucose and mannose incorporation into lipid-linked oligosaccharides and glycoproteins were preceded by decreases in the labeling … the binding and the rate of cell agglutination caused by the plant lectin, concanavalin A. The findings that tiazofurin … [3H]mannose for the formation of glycoproteins … inhibition of IMP dehydrogenase.”
“Interference … [3H]mannose for the formation of glycoproteins was paralleled by an inhibition of [… their lipid-linked oligosaccharide precursors following treatment with cytotoxic concentrations of tiazofurin (100 microM) or mycophenolic acid (10 microM); these actions occurred within 3 … to these agents, with maximal reductions being observed at 12 hr.”
Effects of the inhibitors of IMP dehydrogenase, tiazofurin and mycophenolic acid, on glycoprotein metabolism.
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