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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Mannose
drug:
Mycophenolic Acid
Research Papers that Mention the Interaction
“ MPA , an inhibitor of IMP dehydrogenase, depletes GTP and thereby suppresses transfer of mannose and fucose to proteins.”
Mycophenolic acid suppresses protein N-linked glycosylation in human monocytes and their adhesion to endothelial cells and to some substrates.“ MPA preferentially inhibits the type II isoform of inosine monophosphate dehydrogenase, depletes GTP, suppresses transfer of mannose and fucose to glycoproteins, and prevents lymphocyte proliferation in vivo.”
APOPTOSIS OF SUPERANTIGEN-ACTIVATED T CELLS INDUCED BY MYCOPHENOLATE MOFETIL TREATMENT1“Interference … [3H]mannose for the formation of glycoproteins was paralleled by an inhibition of [3H] mannose …-linked oligosaccharide precursors following treatment with cytotoxic concentrations of tiazofurin (100 microM) or mycophenolic acid (10 microM); these actions occurred within 3 hr of … agents, with maximal reductions being observed at 12 hr.”
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