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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Mannose and Doxorubicin Hydrochloride

Research Papers that Mention the Interaction

Pharmacokinetic studies revealed improved bioavailability, half life and mean residence time of DOX upon mannose conjugation.
Journal of controlled release : official journal of the Controlled Release Society  •  2010  |  View Paper
We demonstrated that surface-modification of the DOX-NPs with both mannose and acid-sensitive sheddable PEG significantly increased the accumulation of DOX in tumors, enhanced the uptake of the DOX by TAMs, but decreased the distribution of DOX in mononuclear phagocyte system (MPS), such as liver.
Molecular pharmaceutics  •  2014  |  View Paper