supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
Research Papers that Mention the Interaction
“Using isolated CCC PM2 DNA, 6-OHDA and ascorbic acid caused strand breaks that were prevented in the presence of mannitol or desferrithiocine.”
Ascorbic acid enhances the effects of 6-hydroxydopamine and H2O2 on iron-dependent DNA strand breaks and related processes in the neuroblastoma cell line SK-N-SH.“The inhibitory effect of ascorbic acid was observed even in the presence of an inhibitor of lipid peroxidation, o‐phenanthroline, or a radical scavenger, mannitol , and the degrading enzymes such as catalase and superoxide dismutase.”
Intracellular Ascorbic Acid Inhibits the Na+‐Ca2+ Exchanger in Cultured Rat Astrocytes“The liver increments and glycogen contents were in the control range for animals fed … containing 30% each of lactose, sorbitol, corn starch and raffinose pentahydrate, 5% ascorbic acid and 15% L-arabinose but the liver glycogen was …% xylose, a diet which was poorly tolerated; 15% mannitol caused a … increment.”
“In the third experiment, the effect of different concentrations of ascorbic acid (0, … l−1) was investigated and the results showed that the application of ascorbic acid (20 … mannitol starvation and heat shock treatment (32 °C) caused remarkable improvement in … embryos and their regeneration ability compared to control treatment.”
Enhancement of microspore embryogenesis induction and plantlet regeneration of sweet pepper (Capsicum annuum L.) using putrescine and ascorbic acid“Furthermore, exogenous addition of ascorbic acid to NaCl or mannitol media induced a significant increase in the contents of ascorbate and glutathione and enzymatic antioxidant activities, in particular, in beans treated with the three highest concentrations of NaCl or mannitol, throughout the period of the experiments (12 days).”
“Protein banding patterns of broad bean seedlings treated with NaCl or mannitol in combination with 4 mM ascorbic acid showed different de novo protein bands, with different molecular weights, at different stages of seedlings growth, with lower levels or a nearly complete absence of the major stress proteins.”
“The … mM ascorbic acid to the stressing media in which the broad bean … combination with either the ionic (NaCl) or osmotic ( mannitol ) stressor induced significant protective changes in the total amount and in the relative composition … in general and in proline, glycine, glutamic, aspartic, alanine and serine in particular.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback