Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago

Possible Interaction: Mannitol and Tryptophan

supplement:

Tryptophan

Research Papers that Mention the Interaction

All the changes except the loss of tryptophan by radiolytic .OH were completely inhibited with mannitol.
Archives of biochemistry and biophysics  •  1991  |  View Paper
In presence of diazabicyclo[2.2.2]octane (DABCO) or D-mannitol , a reduction in the photooxidation of Trp was found, indicating a contribution of type I photoprocess.
European journal of medicinal chemistry  •  2017  |  View Paper
The addition of mannitol had a large impact on most of the Trp positions studied.
Journal of Biological Chemistry  •  2005  |  View Paper
The change in emission signal of the purified enzyme upon mannitol binding (-28%) was 4-fold larger than with EII(mtl) containing tryptophan , demonstrating the known higher sensitivity of this analogue for changes in the microenvironment [Schlesinger, R. (1968) J. Biol.
Biochemistry  •  1999  |  View Paper
Tryptophans at positions 30 and 42 showed changes in fluorescence intensity decay upon binding mannitol , which were reflected in the changes in lifetime distribution patterns.
Biochemistry  •  1997  |  View Paper