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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Manganese
drug:
Phenobarbital
Research Papers that Mention the Interaction
“An increased or decreased enhancement factor for Mn may have contributed to the observed deviations during phenobarbital and thioacetamide treatment.”
Contribution of paramagnetic trace elements to the spin-lattice relaxation time in the liver.“Pretreatment of male rats with phenobarbital markedly decreases while treatment with manganese prolongs the duration of hexobarbital hypnosis in male rats.”
“The administration of phenobarbital (75 mg/kg) to rats for 3 days produced significant increases in liver microsomal copper, manganese , and zinc levels.”
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