Allen Institute for Artificial Intelligence logo

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Manganese and Phenobarbital



Research Papers that Mention the Interaction

An increased or decreased enhancement factor for Mn may have contributed to the observed deviations during phenobarbital and thioacetamide treatment.
Investigative radiology  •  1985  |  View Paper
Pretreatment of male rats with phenobarbital markedly decreases while treatment with manganese prolongs the duration of hexobarbital hypnosis in male rats.
Research communications in chemical pathology and pharmacology  •  1983  |  View Paper
The administration of phenobarbital (75 mg/kg) to rats for 3 days produced significant increases in liver microsomal copper, manganese , and zinc levels.
Cancer research  •  1972  |  View Paper