Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago

Possible Interaction: Manganese and Morphine

supplement:

Manganese

Research Papers that Mention the Interaction

Harris et a[. [I21 have demonstrated that prior administration of calcium (as well as magnesium or manganese ) to mice prevented the analgesic effect of a single dose of morphine and also that calcium was a more effective antagonist in morphinetolerant mice than in nontolerant animals.
Biochemical pharmacology  •  1977  |  View Paper
Intraperitoneal pretreatments with … quaternary opiate antagonist MN (which does not cross the blood-brain barrier effectively) … conditioned place aversions produced by low IP doses of morphine (0.05 mg/kg), but not the place aversions produced by lithium … IP), or by high doses of naloxone (10 mg/kg SC).
Pharmacology Biochemistry and Behavior  •  1987  |  View Paper
The effect of morphine was enhanced by manganese ion in the presence of normal Na+.
European journal of pharmacology  •  1977  |  View Paper
She imnproved considerably at first under the use of manganese , with s'Mall doses of morphia ; but the improvement lasted only a fe* days.
British medical journal  •  1888  |  View Paper