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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Manganese
drug:
Methylphenidate
Research Papers that Mention the Interaction
“We then prospectively assessed the impact of naturalistic treatment with MPH and determined that Mn concentrations were significantly reduced from baseline values following MPH exposure.”
Manganese in children with attention-deficit/hyperactivity disorder: relationship with methylphenidate exposure.“In addition, the effect of MPH was qualitatively different for the Mn-exposed versus control animals across a range of behavioral measures of inhibitory control and attention, as well as dendritic spine density in the mPFC, suggesting that postnatal Mn exposure alters catecholaminergic systems modulating these behaviors.”
Methylphenidate alleviates manganese-induced impulsivity but not distractibility.
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