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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
Research Papers that Mention the Interaction
“Activation of the catalytic unit of adenylate cyclase with manganese produced 49% of normal activity; manganese plus forskolin produced 54% of normal adenylate cyclase activity.”
New form of pseudohypoparathyroidism with abnormal catalytic adenylate cyclase.“The contractile inhibitions caused by 30 microM db cAMP and 0.2 microM forskolin were enhanced after pretreatment with 0.35 mM Mn for 10 min, whereas the inhibition caused by 100 mU relaxin underwent enhancement or attenuation.”
Influence of intracellular Mn on the contractile inhibition caused by db cAMP, forskolin, and porcine relaxin in the circular muscle of the estrogen-treated rat uterus.“The PKA activity was increased by 39 and 6% of the control, when 30 microM db cAMP … 0.1 microM forskolin were applied, respectively; the PKA activity in response to db cAMP and forskolin was reduced and enhanced, respectively, when the tissues were pretreated with 0.6 mM Mn.”
“The contractile depression caused by db cAMP was reduced and by forskolin was enhanced by pretreatment of the tissue with 0.6 mM Mn for 30 min.”
“In contrast, the depression of contraction by isoprenaline or forskolin was enhanced by pretreatment with either Mg or Mn.”
“The effect of forskolin on the activation by manganese ion was neither synergistic nor inhibitory but was additive in AH66F cells.”
“The adenylate cyclase response to forskolin at the low-affinity site is greater with Mn than with Mg.(ABSTRACT TRUNCATED AT 250 WORDS)”
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