Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago

Possible Interaction: Manganese and Aspartate

supplement:

Manganese

Research Papers that Mention the Interaction

Manganese treatment produced increased aspartate (P < 0.01) in the manganese and 6-OHDA treated striatum.
Neurotoxicology  •  2002  |  View Paper
However sodium and the divalent cations copper, cobalt, zinc, cadmium, and manganese decrease binding to this N‐methyl‐D‐aspartate site.
Journal of neurochemistry  •  1987  |  View Paper
Kinetic studies using Mn and Ca ions indicate that the k values (… compared with the value obtained using Mg; however, the K values for aspartate … Mn and Ca were significantly decreased compared with those obtained using Mg ion (… and 5.6 and 5.8 times for Ca ion, respectively).
The Journal of Biological Chemistry  •  1995  |  View Paper
Glutamate, aspartate , alanine and glycine inhibit GS activity in the presence of both Mg and Mn.
Sinergistic inhibition was observed under the combined effect of amino acids on GS in the presence of Mn and aspartate or alanine.
Biokhimiia  •  1976  |  View Paper