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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Manganese and 2-Methoxyestradiol

Research Papers that Mention the Interaction

It has been reported in the literature that the endogenous estrogen metabolite 2-methoxyestradiol (2-ME) inhibits both manganese and copper,zinc superoxide dismutases (Mn and Cu,Zn SODs) and that this mechanism is responsible for 2-ME's ability to kill cancer cells.
Archives of biochemistry and biophysics  •  2001  |  View Paper