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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Magnesium
drug:
Vecuronium
Research Papers that Mention the Interaction
“We conclude that magnesium pretreatment increased the neuromuscular potency of vecuronium , in addition to modifying the time course of its neuromuscular block.”
Interaction of magnesium sulphate with vecuronium-induced neuromuscular block.“ Magnesium significantly shortened the onset time of vecuronium (154.0 +/- 25.9, 162.0 +/- 22.4 sec. in Mg1 & Mg2 Gs respectively vs. 227.4 +/- 10.9 sec. in control), prolonged its clinical duration (44.7 +/- 3.2, 46.4 +/- 5.1 min.”
“Mean arterial blood pressure and heart rate were lower in magnesium groups with lowest value in Mg2 G. It is concluded that magnesium 50 mg kg(-1) bolus followed by 8 mg kg(-1) h(-1) leads to significant reductions in intraoperative propofol and vecuronium and postoperative fentanyl consumption.”
“Although serum magnesium value was not beyond therapeutic levels (3.3 mEq.l-1), the neuromuscular blocking effects with vecronium were strengthened.”
“The duration of action of vecuronium was significantly longer in the magnesium group than in the control group.”
“The onset time of vecuronium was significantly shorter in the magnesium group than in the control group.”
Effects of pretreatment with magnesium on muscle relaxation and cardiovascular responses in tracheal intubation using the priming principle for vecuronium
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