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Last Updated: 6 months ago

Possible Interaction: Magnesium and Vecuronium

supplement:

Magnesium

Research Papers that Mention the Interaction

We conclude that magnesium pretreatment increased the neuromuscular potency of vecuronium , in addition to modifying the time course of its neuromuscular block.
British journal of anaesthesia  •  1995  |  View Paper
Magnesium significantly shortened the onset time of vecuronium (154.0 +/- 25.9, 162.0 +/- 22.4 sec. in Mg1 & Mg2 Gs respectively vs. 227.4 +/- 10.9 sec. in control), prolonged its clinical duration (44.7 +/- 3.2, 46.4 +/- 5.1 min.
Mean arterial blood pressure and heart rate were lower in magnesium groups with lowest value in Mg2 G. It is concluded that magnesium 50 mg kg(-1) bolus followed by 8 mg kg(-1) h(-1) leads to significant reductions in intraoperative propofol and vecuronium and postoperative fentanyl consumption.
Journal of the Egyptian Society of Parasitology  •  2007  |  View Paper
Although serum magnesium value was not beyond therapeutic levels (3.3 mEq.l-1), the neuromuscular blocking effects with vecronium were strengthened.
Masui. The Japanese journal of anesthesiology  •  1997  |  View Paper
The duration of action of vecuronium was significantly longer in the magnesium group than in the control group.
The onset time of vecuronium was significantly shorter in the magnesium group than in the control group.
Journal of Anesthesia  •  2006  |  View Paper