“ Magnesium reduced total infarct volume by 25% (nonsignificant), tirilazad by 48% (P<0.05), and combination therapy by 59% (P<0.05) compared with control data.”
“We examined the hypothesis that concurrent administration of tirilazad , a well-known antioxidant, and magnesium , an antagonist of calcium and excitatory amino acids, would result in a synergistic neuroprotective effect.”