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Last Updated: 3 years ago

Possible Interaction: Magnesium and Thyroxine

supplement:

Magnesium

Research Papers that Mention the Interaction

Rats with thyroid-depressing lesions required only 1.0 μg Na l-thyroxine/100 gm./day to prevent thyroid secretion (loss of incorporated I131) in the presence of 5–10 mg.
Endocrinology  •  1961  |  View Paper
Brain magnesium was found to be significantly decreased after antithyroid treatment and increased to a lesser extent after thyroxine administration.
The administration of thyroxine produces a significant increase in the copper, magnesium , iron and zinc contents of liver, with a concomitant decrease of heart iron.
Journal of clinical chemistry and clinical biochemistry. Zeitschrift fur klinische Chemie und klinische Biochemie  •  1982  |  View Paper
Vitale et al. (4) have demonstrated that magnesium will also partially overcome the growth-inhibiting action of thyroxine administration.
The Journal of biological chemistry  •  1958  |  View Paper
It was suggested that the increased requirement for magnesium in the cold might be related to thyroid activity (I), since thyroxine uncouples oxidative phosphorylation in vitro, and that magnesium prevents this uncoupling effect (3, 4).
The Journal of biological chemistry  •  1957  |  View Paper