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“Rats with thyroid-depressing lesions required only 1.0 μg Na l-thyroxine/100 gm./day to prevent thyroid secretion (loss of incorporated I131) in the presence of 5–10 mg.”
“ Brain magnesium was found to be significantly decreased after antithyroid treatment and increased to a lesser extent after thyroxine administration.”
“The administration of thyroxine produces a significant increase in the copper, magnesium , iron and zinc contents of liver, with a concomitant decrease of heart iron.”
The Journal of biological chemistry • 1958 | View Paper
“It was suggested that the increased requirement for magnesium in the cold might be related to thyroid activity (I), since thyroxine uncouples oxidative phosphorylation in vitro, and that magnesium prevents this uncoupling effect (3, 4).”