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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Magnesium Sulfate
supplement:
Thiamine Pyrophosphate
Research Papers that Mention the Interaction
“The apparent Km for thiamine diphosphate (thiamin-P2) in the presence of 5 mM MgSO4 was increased by a factor of 10 (84 microM in Mes/KOH buffer) and the tetrameric mutant protein was less stable, as indicated by urea denaturation experiments.”
The replacement of Trp392 by alanine influences the decarboxylase/carboligase activity and stability of pyruvate decarboxylase from Zymomonas mobilis.
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