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Last Updated: 2 years ago

Possible Interaction: Magnesium Sulfate and Calcium Supplement

Research Papers that Mention the Interaction

Experimental studies suggested that MgSO4 inhibits excitatory amino acid release, blocks N-methyl-D-aspartate (NMDA) receptors and prevents calcium entry into the cell.
Neurological research  •  2006  |  View Paper
Magnesium sulfate decreased inositol trisphosphate production in calcium-containing media but had no additional effect in calcium-free media.
American journal of obstetrics and gynecology  •  2002  |  View Paper
Using a novel ion‐selective electrode, we have shown that there is over a 100% increase in venous serum levels of ionized Mg during intravenous MgSO4 therapy of preeclamptic patients.
Acta obstetricia et gynecologica Scandinavica  •  1995  |  View Paper
Similarly, magnesium sulphate , which acts by preventing an increase in intracellular calcium , is rarely used.
Anaesthesia  •  1994  |  View Paper
Urinary losses of calcium in the magnesium sulfate group , approximately 800 to 900 mg/day, were substantial.
Urinary output of magnesium, calcium , and copper was significantly greater in the magnesium sulfate group than in the control group throughout the study.
American journal of obstetrics and gynecology  •  1992  |  View Paper
Urinary calcium concentration increased 4.5-fold during magnesium sulfate infusion, and the urinary calcium excretion rate was 3 times that observed in controls.
Obstetrics and gynecology  •  1981  |  View Paper
Addition of a dose of magnesium sulphate to the infusion antagonises the effect of gastric acid secretion caused by calcium.
Acta hepato-gastroenterologica  •  1976  |  View Paper
Patients receiving MgSO4 (1 or 2 gm) had increases in Mg+ + and reduction of Ca++ and K+ even when muscle fasciculations were evident.
Canadian Anaesthetists' Society journal  •  1970  |  View Paper
These results suggest that magnesium sulfate hardly affects the electrical vulnerability of the heart during haloperidol overdose, but may block the calcium , potassium and sodium channels, which may explain its antiarrhythmic action.
Japanese circulation journal  •  2000  |  View Paper
In addition, the limb rigidity that accompanies this increase in calcium was prevented by MgSO4 pretreatment.
Anesthesiology  •  1990  |  View Paper