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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Magnesium
drug:
Spironolactone
Research Papers that Mention the Interaction
“The results suggest that spironolactone administration decreases the renal excretion of magnesium and potassium in an equivalent manner.”
Changes of fractional renal clearance of magnesium after spironolactone administration in normal subjects“In the control group, oral administration of spironolactone (200 mg daily for 5 days) resulted in a significant decrease in the mean renal excretion of both magnesium and potassium.”
“The study suggests that spironolactone decreases magnesium excretion in normal subjects and antagonizes the magnesiuric effect of frusemide in patients with liver cirrhosis and secondary aldosteronism.”
“ Spironolactone reduced the urinary magnesium in 2 patients with primary aldosteronism.”
“Animals treated with magnesium after the 176-dB SPL exposure had a significant reduction in hair cell loss in the basal region.”
“The threshold shifts of the 170-dB SPL group that received magnesium were significantly lower than those of controls after 2 and 7 days of recovery, but no significant difference was evidenced at 14 days in this group, nor at any time in the 176-dB SPL group.”
Therapeutic efficacy of magnesium after acoustic trauma caused by gunshot noise in guinea pigs
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