Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago

Possible Interaction: Magnesium and Spermine

supplement:

Magnesium

Research Papers that Mention the Interaction

In keeping with the known role of polyamines as counterions in RNA folding, we have found that concentrations of spermine as low as 1 microM facilitate first-order Cis cleavage and decrease the concentration of magnesium required for optimal cleavage of the VS ribozyme.
Biochemistry  •  1998  |  View Paper
High rates of correct aminoacylation are achieved in the presence of physiological concentrations of magnesium (1.0 mM) plus spermine (0.2 mM).
The Journal of biological chemistry  •  1981  |  View Paper
The polyamine spermine stabilizes some, but not all, of the structural features stabilized by magnesium at 44 degrees C, and the combination of magnesium and spermine , at low levels, is more effective than either cation alone in stabilizing tRNA structure.
Biochimica et biophysica acta  •  1977  |  View Paper