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British journal of anaesthesia • 2005 | View Paper
“Results Part I: The mean propofol infusion rate in the magnesium group (81.81 ± 13.09 &mgr;g · kg−1 · min−1) was significantly less than in the control group (167.57 ± 47.27).”
“Propofol and propofol EDTA produced a statistically significant decrease from baseline in serum concentrations of ionized calcium and magnesium during infusion (P <0.05), but with no apparent clinical effect.”
“Infusion of 30 mg/kg magnesium sulfate may reduce the Cp50cal of propofol at loss of consciousness, which implies that magnesium may enhance the pharmacological effects of propofol.”