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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Magnesium
drug:
Phospholipids
Research Papers that Mention the Interaction
“ Magnesium depletion of the erythrocytes considerably decreases the outward rate of both aminophospholipids to values close to that of phosphatidylcholine.”
Measurement of outward translocation of phospholipids across human erythrocyte membrane.“Measurements with a fluorescent probe TMA-DPH and its sensitized fluorescence with tryptophan residues as donors revealed that magnesium increased the order of the membrane phospholipids both in the lipid annulus and in the bulk phase.”
Mg2+-induced changes of lipid order and conformation of (Na+ + K+)-ATPase.“Serum analysis indicated that dietary low Mg supplementation decreased cholesterol levels and increased phospholipid concentrations significantly.”
“Liposomes of acidic phospholipids or phosphatidylcholine containing anionic amphipaths prevented the ATP plus Mg 2 + -induced decrease of ATPase activity in Mg-ATP particles which have a high content of ATPase inhibitor.”
“Of these three NPPases (acid, Mg2+‐activated, and K+, Mg2+‐activated), only K‐Mg NPPase was stimulated about two‐fold by phospholipid and was inhibited by unsaturated neutral lipids and fatty acids.”
“These results indicated a possible role of anionic phospholipids in mediating binding of MTR and its magnesium complex to the cell surface membranes before reaching the target DNA.”
Membrane interaction of an antitumor antibiotic, mithramycin, with anionic phospholipid vesicles.
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