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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Magnesium Oxide
drug:
Gabapentin
Research Papers that Mention the Interaction
“In the pharmacokinetics of gabapentin , concomitant magnesium oxide reduced the intestinal absorption of gabapentin. (”
[Clinical pharmacology and pharmacoepidemiology for medication safety in clinical settings].“In conclusion, concomitant MgO decreased the gabapentin exposure through the reduction of intestinal absorption extent and rate.”
“The C(max), T(max) and AUC(0-∞) of gabapentin + MgO were significantly lower than that of gabapentin alone (by 33%, 36% and 43%, respectively) and gabapentin + omeprazole (by 29%, 46% and 40%, respectively).”
“The gabapentin BA in the MgO treatment was significantly lower, by 32% and 39%, compared to the gabapentin alone and with omeprazole treatment, respectively.”
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