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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Magnesium
drug:
Lomefloxacin
Research Papers that Mention the Interaction
“When LFLX was orally administered concomitantly with aluminum- and magnesium-containing antacids under fasting conditions, its level in plasma decreased by one-half and its area under the concentration-time curve was reduced by 40% compared with the levels observed after treatment with LFLX alone.”
Effect of antacid on absorption of the quinolone lomefloxacin“It was observed that availability of lomefloxacin was depressed in presence of … presence of Fe2+ in simulated intestinal juice, while many metals like magnesium , chromium, iron (both Fe2+ … the availability of lomefloxacin at blood pH. Furthermore, the availability of lomefloxacin alone … was reduced as compared to simulated gastric juice.”
In vitro availability of lomefloxacin hydrochloride in presence of essential and trace elements.
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