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Last Updated: 2 years ago

Possible Interaction: Magnesium and Gentamicin

supplement:

Magnesium

Research Papers that Mention the Interaction

Gentamicin caused a statistically significant post-infusion increase in fractional excretion of sodium and magnesium and in the urine calcium to urine creatinine ratio.
Pediatric Nephrology  •  2003  |  View Paper
A number of drugs have been shown to alter magnesium handling ; these include antibiotics such as gentamicin , antineoplastic agents such as cisplatin and immunological suppressive drugs such as cyclosporin.
Magnesium  •  1986  |  View Paper
These observations suggest that serum calcium, magnesium , and potassium should be monitored during gentamicin therapy.
Two patients developed severe hypomagnesemia, hypocalcemia, and hypokalemia as a result of renal wasting of magnesium and potassium shortly after being treated with large doses of gentamicin.
Annals of internal medicine  •  1975  |  View Paper
This reduction in nephrotoxicity was probably due to competition of binding between magnesium and gentamicin to the renal membrane.
Nephron  •  1989  |  View Paper
This study investigated the efficacy and safety of NM block caused by the administration of high concentrations of magnesium in combination with ropivacaine, gentamicin , and rocuronium.
Korean journal of anesthesiology  •  2015  |  View Paper
These effects were also antagonized by magnesium and were very similar to those seen with EDTA and gentamicin.
Antimicrobial Agents and Chemotherapy  •  1988  |  View Paper
It thus appears that a high magnesium content, which is necessary for pyocyanin production, also increases the resistance of this organism to gentamicin.
Journal of clinical pathology  •  1969  |  View Paper