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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Magnesium
drug:
Gentamicin
Research Papers that Mention the Interaction
“ Gentamicin caused a statistically significant post-infusion increase in fractional excretion of sodium and magnesium and in the urine calcium to urine creatinine ratio.”
Acute effects of gentamicin on urinary electrolyte excretion in neonates“A number of drugs have been shown to alter magnesium handling ; these include antibiotics such as gentamicin , antineoplastic agents such as cisplatin and immunological suppressive drugs such as cyclosporin.”
“These observations suggest that serum calcium, magnesium , and potassium should be monitored during gentamicin therapy.”
“Two patients developed severe hypomagnesemia, hypocalcemia, and hypokalemia as a result of renal wasting of magnesium and potassium shortly after being treated with large doses of gentamicin.”
“This reduction in nephrotoxicity was probably due to competition of binding between magnesium and gentamicin to the renal membrane.”
Effect of magnesium diet in gentamicin-induced acute renal failure in rats.“This study investigated the efficacy and safety of NM block caused by the administration of high concentrations of magnesium in combination with ropivacaine, gentamicin , and rocuronium.”
The effect of high concentration of magnesium with ropivacaine, gentamicin, rocuronium, and their combination on neuromuscular blockade“These effects were also antagonized by magnesium and were very similar to those seen with EDTA and gentamicin.”
“It thus appears that a high magnesium content, which is necessary for pyocyanin production, also increases the resistance of this organism to gentamicin.”
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