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“Specific binding of [3H]forskolin (10 nM) was augmented by the addition of magnesium , and in the presence of 5 mM MgCl2, sodium fluoride (NaF) increased further the specific binding in a concentration-dependent manner.”
“ Magnesium also markedly affected the affinity of the enzyme system for forskolin.”
“Studies of the interaction of forskolin with magnesium revealed that forskolin resulted in a dose dependent increase in the affinity of adenylate cyclase for magnesium.”