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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Magnesium Chloride
drug:
Spermine
Research Papers that Mention the Interaction
“ Spermine also caused a shift in the MgCl2 saturation curve from sigmoidal to hyperbolic, lowering the Mg2+ concentration required for optimum kinase activity to the physiological range.”
Phosphatidylinositol-4-phosphate kinase from rat brain. Activation by polyamines and inhibition by phosphatidylinositol 4,5-bisphosphate.“At 2 mM MgCl2 , 1 mM spermine enhanced the enzyme activity 3-times.”
“Spermidine and spermine can partially replace the MgCl2 requirement for CDP and ADP reduction.”
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