Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 4 years ago

Possible Interaction: Magnesium Cation and Manganese Cation (2+)

Research Papers that Mention the Interaction

The presence of Mg2+ (2 mm) greatly lowered the apparent K m values for Mn2+ (by 144-fold in the presence of DTT and by 9.4-fold in the absence of DTT) and Co2+ (by 230-fold).
The Journal of Biological Chemistry  •  2001  |  View Paper
Both the Zn(II) in the i site and the Mg(II) in i + 1 are displaced by Mn(II).
Biochemistry  •  1990  |  View Paper
The kinetic properties observed with Mn(II ) as the activating divalent cation were somewhat different than those observed in the presence of Mg(II).
The Journal of biological chemistry  •  1971  |  View Paper