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Last Updated: 3 months ago

Possible Interaction: M-Chlorophenylpiperazine and Adrenocorticotropic Hormone

Research Papers that Mention the Interaction

At the dose of 0.5 mg/kg, m-CPP caused increase in ACTH , cortisol, TSH and aldosterone concentrations.
m-CPP 0.25 mg/kg avoided decreases in ACTH , cortisol and TSH concentrations; these responses were significant.
Psychopharmacology  •  1998  |  View Paper
m-CPP also produced statistically significant increases in temperature, systolic and diastolic blood pressure, heart rate, and in plasma concentrations of adrenocorticotropic hormone , cortisol, prolactin and norepinephrine.
Psychopharmacology  •  1997  |  View Paper
RESULTS Me a-chlorophenylpiperazine pr oduced (1) significant increases in "activation-euphoria" ratings only in depressed patients with SAD in the untreated condition and (2) blunted cor ticotropin an d norepinephrine responses in patients with SAD compared with controls across both light treatment conditions.
Archives of general psychiatry  •  1997  |  View Paper
Non-linear dose-response relationships between MCPP and ACTH , cortisol and prolactin response were found.
Psychopharmacology  •  1990  |  View Paper
We have recently demonstrated that a single administration of m-chlorophenylpiperazine (m-CPP, a preferential 5-HT2C receptor agonist) produces tolerance to its stimulatory effect on adrenocorticotropic hormone (ACTH) concentrations when challenged 24 h later with the same dose of m-CPP.
European journal of pharmacology  •  1996  |  View Paper
ACTH induced (after 120 and 180 min) significant increases in HMG-CoA reductase activity with a latent period of 60 min for both McNaF and McPP preparations.
Journal of steroid biochemistry  •  1986  |  View Paper