supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 2 years ago
Research Papers that Mention the Interaction
“Because lysine can act as a competitive inhibitor of the conversion of arginine to ornithine and urea , an increased level of plasma lysine may therefore inhibit the urea cycle.”
Hereditary metabolic disorders of the urea cycle.“Increasing the dietary SID Val Lys ratio linearly increased N retention (P < 0.04) and quadratically decreased plasma concentrations of urea (P < 0.01).”
Estimates of the optimum dietary ratio of standardized ileal digestible valine to lysine for eight to twenty-five kilograms of body weight pigs.“ Urea supplementation depressed plasma Lys , doubled plasma Cit with soybean meal and conglomerated corn starters, but depressed plasma Cit with roasted soybeans and conglomerated corn starters.”
“Several unassigned side-chain NH's of arginine or lysine are highly protected from exchange by urea , suggesting that they are the location of urea binding sites on the surface of the molecule.”
“A deficiency of arginine and lysine increased urea and citrate excretions to a greater extent than either deficiency alone.”
“Surgery increased the concentration gradient (release) of urea across liver by 60%, the glucose gradient (release) by 35%, and doubled the concentration gradients (uptake) across liver of alanine, arginine, glycine, lysine , proline, serine, and threonine, and decreased their plasma concentrations.”
Effects of hysterectomy and semi-starvation on amino-acid gradients across liver, muscle and gut in rats.
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback