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Last Updated: 2 years ago

Possible Interaction: Lysine and S-Adenosylmethionine

supplement:

Lysine

Research Papers that Mention the Interaction

Plant monofunctional aspartate kinase is unique among all aspartate kinases, showing synergistic inhibition by lysine and S‐adenosyl‐l‐methionine (SAM).
The FEBS journal  •  2007  |  View Paper
binding l-lysine has been … measured with SAM bound to the cluster and l-alanine in place of l-lysine, with S-adenosyl-l-homocysteine (SAH) bound to the … to the cluster in the presence of l-alanine or of l-alanine and ethylamine in place of l-lysine.
Biochemistry  •  2007  |  View Paper
A loop involved in the binding of Lys and S-adenosylmethionine provides an explanation for the synergistic inhibition by these effectors.
The Plant Cell Online  •  2006  |  View Paper
The lysine can activate one of the catecholic hydroxyl groups for a nucleophilic attack on the active methyl group of the coenzyme S-adenosyl-l-methionine (AdoMet).
J. Comput. Aided Mol. Des.  •  1998  |  View Paper
In addition, we found that methionine analogs and high concentrations of amino acids which are known to affect SAM synthesis in other bacteria, such as threonine, lysine , and isoleucine, also caused reduced cellular levels of SAM and blocked fruiting body formation in M. xanthus.
Journal of bacteriology  •  1995  |  View Paper
Inhibition by lysine was synergistically increased by S-adenosylmethionine , which by itself had no effect on activity.
Plant physiology  •  1989  |  View Paper