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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“Using a combination of immunohistochemistry, Western blot, and whole cell patch-clamp recording in rat midbrain slices, we show that morphine increased HDAC2 activity in VTA DA neurons and reduced histone H3 acetylation at lysine 9 (Ac-H3K9) in the VTA 24 h after the injection.”
“In contrast to the block of non-narcotic analgesics, l-lysine potentiated the antinociceptive effects of morphine.”
“In normal facial neurons, the accumulation of lysine into the nucleus and nucleolus was significantly lower 60 min after morphine administration.”
“Despite the similarity in specific incorporation of lysine into brain protein in both strains of control rat, morphine treatment caused a much more marked inhibition of incorporation of lysine in the Wistar rats.”
“In the cortical gray matter, morphine elevated the SA of lysine significantly in both strains, although the rate of decrease of SA with increasing time after injection was different in the two strains.”
“ Morphine elevated the levels of specific accumulation of lysine into the cortical free amino acid pool in both strains of rat.”
STRAIN DIFFERENCES IN THE RESPONSE TO MORPHINE ON INCORPORATION OF 3 H‐LYSINE INTO RAT BRAIN PROTEIN“ Morphine inhibited lysine accumulation in Wistar Purkinje neurons but stimulated it in the Sprague‐Dawley animals.”
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