supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
supplement:
Lysine
drug:
Decitabine
Research Papers that Mention the Interaction
“The occupancy of the activating histone mark dimethylated lysine 4 of H3 at Pd was enhanced by DAC and MS-275 but not ATO.”
Three Epigenetic Drugs Up-Regulate Homeobox Gene Rhox5 in Cancer Cells through Overlapping and Distinct Molecular Mechanisms“Here, we show that the level … trimethylation of histone H3 on lysine 27 , a hallmark of the activity of EZH2, a component of repressive Polycomb Group (PcG) complexes … PRC2, is increased on reactivation of the silenced allele by either the DNA demethylating agent 5-azadeoxycytidine or the … inhibitor splitomicin.”
“Using a streamlined mass spectrometric approach to determine changes in modification states in the first 50 … of histone H3, we found a decrease in the global methylation states of H3.1 at Lys 9 , Lys 14, and Lys 27 after inhibition of DNA methyltransferases by 5-aza-2'-deoxycytidine.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback