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Discover Supplement-Drug Interactions

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Last Updated: a year ago

Possible Interaction: Lysine and Decitabine



Research Papers that Mention the Interaction

The occupancy of the activating histone mark dimethylated lysine 4 of H3 at Pd was enhanced by DAC and MS-275 but not ATO.
Molecular Pharmacology  •  2009  |  View Paper
Here, we show that the level … trimethylation of histone H3 on lysine 27 , a hallmark of the activity of EZH2, a component of repressive Polycomb Group (PcG) complexes … PRC2, is increased on reactivation of the silenced allele by either the DNA demethylating agent 5-azadeoxycytidine or the … inhibitor splitomicin.
Human molecular genetics  •  2014  |  View Paper
Using a streamlined mass spectrometric approach to determine changes in modification states in the first 50 … of histone H3, we found a decrease in the global methylation states of H3.1 at Lys 9 , Lys 14, and Lys 27 after inhibition of DNA methyltransferases by 5-aza-2'-deoxycytidine.
Analytical biochemistry  •  2010  |  View Paper