Possible Interaction: Lysine and Calcium Supplement

“The bioavailability of calcium was higher in samples with lysine and vitamin K compared with samples that contained eggshell alone.”

“Adding Lys to the NM based diet significantly increased the Ca concentration in serum compared with NM or HMN diets.”

“The introduction of additional cross-links with L-lysine resulted in a significant reduction of calcium in all tissues (maximally 42.5%, p = 0.0003 in leaflets; 79.3%, p = 0.005 in pericardium; and 49.6%, p <0.0001 in aortic wall; Student's t-test).”

“Our studies suggest that calcium is in general essential … the formation of osmium black, but also that lysine is reactive even in the absence of calcium and that a few amino acids--such as tryptophan, ornithine, cysteine, and aspartic acid--are only slightly reactive in the absence of calcium.”

“A high dietary content of calcium (25.9 vs 11.8 g/kg) reduced chick performance and the digestibility of glutamic acid, leucine and phenylalanine but increased the digestibility of lysine and histidine.”

“In the presence of calcium ions , the susceptibility of these sites to trypsin decreased and limited proteolysis occurred at Lys 77 as already reported by other workers.”

“D- and L-amino acids (arginine, lysine ) and hydroxylated molecules (sorbitol, ethyl-ethanolamine), all of which increase the intestinal transfer of calcium , are phosphorylated by jejunal and ileal microvilli.”

“Incorporation of radioactive lysine into myoglobin rose with increased medium concentrations of calcium , but was not directly related to cell fusion.”

“We hypothesized that chloride, another factor often associated with isolated proteins, and another amino acid, lysine , affect utilization of calcium.”

“Wasserman et al. (16) later reported that lysine and arginine markedly stimulated calcium ab sorption.”