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Last Updated: 3 years ago

Possible Interaction: Lysine and Alpha-Ketoglutaric Acid

supplement:

Lysine

Research Papers that Mention the Interaction

Abstract It was shown previously that lysine was degraded in the mitochondria in the presence of α-ketoglutarate and, under these conditions, saccharopine accumulated (1).
Biochemical and biophysical research communications  •  1967  |  View Paper
The enzymatic formation of HC from α-ketoglutarate plus acetyl-coenzyme A in cell-free extracts of the same organism was also inhibited by lysine.
Journal of bacteriology  •  1967  |  View Paper
The level of α-ketoglutarate influences both the rate and extent of conversion of lysine to β-lysine, but the system does not require substrate levels of α-ketoglutarate.
The Journal of biological chemistry  •  1966  |  View Paper