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Last Updated: 3 years ago

Possible Interaction: Lysergic Acid Diethylamide and Melatonin

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drug:

Lysergic Acid Diethylamide

supplement:

Melatonin

Research Papers that Mention the Interaction

“These observations, coupled with the demonstration that LSD is a directly acting and potent inhibitor of neural activity of the serotonin-containing neurons of the DRN 14, led us to examine the behavioral effect of LSD on SPA.”

Reduction of stimulation-produced analgesia by lysergic acid diethylamide, a depressor of serotonergic neural activity

Brain Research • 1977 | View Paper

“Large doses of LSD induce a prolonged inhibition of the serotonin-containing neurones1; this inhibition may account for the reduced metabolism of brain serotonin observed after injections of LSD5–8.”

Comparison of Effects of LSD and Amphetamine on Midbrain Raphe Units

Nature • 1969 | View Paper

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