Allen Institute for Artificial Intelligence logo

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 6 months ago

Possible Interaction: Lycopene and Glabridin





Research Papers that Mention the Interaction

We conclude that lycopene acts synergistically, as an effective antioxidant against LDL oxidation, with several natural antioxidants such as vitamin E, the flavonoid glabridin , the phenolics rosmarinic acid and carnosic acid, and garlic.
When lycopene (5 micromol/liter) was added to LDL in combination with glabridin , rosmarinic acid, carnosic acid, or garlic, synergistic antioxidative effects were obtained against LDL oxidation induced either by copper ions or by the radical generator AAPH.
Antioxidants & redox signaling  •  2000  |  View Paper
Glabridin … lycopene by 38 and 52%, respectively, after 0.5 h of LDL oxidation with AAPH, but failed to protect vitamin E. The in vivo and … particle and subsequent protection of LDL from oxidation by inhibiting the formation of lipid peroxides and oxysterols, and by protecting LDL associated carotenoids.
Atherosclerosis  •  1998  |  View Paper