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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Lovastatin
supplement:
Very Long Chain Fatty Acid
Research Papers that Mention the Interaction
“ Lovastatin , a 3-hydroxy-3-methyllutaryl-coenzyme A (HMG-CoA) reductase inhibitor, was reported o reduce cholesterol and saturated VLCFA levels in adult ALD atients [2].”
Effect of statin treatment on adrenomyeloneuropathy with cerebral inflammation: A revisit“Based on observations in skin fibroblasts [4], it was sugested that lovastatin reduces C26:0 in skin fibroblasts of patients ith X-ALD (it should be noted that only the C26/C22 ratio as reported, and not the absolute C26 levels).”
“We showed that ovastatin indeed reduces C26:0 in the plasma of patients because ow Density Lipoprotein (LDL) particles which are the vehicle for 26:0 transport are lowered by lovastatin.”
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