Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago

Possible Interaction: Lovastatin and Very Long Chain Fatty Acid

Research Papers that Mention the Interaction

Lovastatin , a 3-hydroxy-3-methyllutaryl-coenzyme A (HMG-CoA) reductase inhibitor, was reported o reduce cholesterol and saturated VLCFA levels in adult ALD atients [2].
Clinical Neurology and Neurosurgery  •  2013  |  View Paper
Based on observations in skin fibroblasts [4], it was sugested that lovastatin reduces C26:0 in skin fibroblasts of patients ith X-ALD (it should be noted that only the C26/C22 ratio as reported, and not the absolute C26 levels).
We showed that ovastatin indeed reduces C26:0 in the plasma of patients because ow Density Lipoprotein (LDL) particles which are the vehicle for 26:0 transport are lowered by lovastatin.
Clinical Neurology and Neurosurgery  •  2013  |  View Paper