“Based on observations in skin fibroblasts [4], it was sugested that lovastatin reduces C26:0 in skin fibroblasts of patients ith X-ALD (it should be noted that only the C26/C22 ratio as reported, and not the absolute C26 levels).”
“We showed that ovastatin indeed reduces C26:0 in the plasma of patients because ow Density Lipoprotein (LDL) particles which are the vehicle for 26:0 transport are lowered by lovastatin.”