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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Lovastatin and Progesterone

supplement:

Progesterone

Research Papers that Mention the Interaction

Now, lovastatin and simvastatin, which strongly inhibited sterol synthesis, significantly attenuated the secretion of progesterone.
So under conditions in which the cholesterol pools were decreased, lovastatin and simvastatin attenuated the progesterone secretion, whereas pravastatin did not.
Biochimica et biophysica acta  •  1996  |  View Paper
Mevinolin (12 microM) inhibited the production of 17 alpha-hydroxyprogesterone from progesterone and that of androstenedione from 17 alpha-hydroxyprogesterone, while 25-hydroxycholesterol to progesterone and pregnenolone to progesterone conversions were unimpaired.
Endocrinology  •  1989  |  View Paper