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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“ Losartan (10 microg/100 nl) or ZD 7155 (5 microg/100 nl) into the RVLM reduced the pressor response to l-glutamate (5+/-3 and 33+/-4mm Hg, respectively) or angiotensin II (5+/-3 and 6+/-2mm Hg, respectively) into the RVLM.”
“ Losartan (100 microg/1 microl) or ZD 7155 (50 microg/1 microl) injected into the LV reduced the pressor responses to l-glutamate into the RVLM (22+/-5 and 26+/-7mm Hg, respectively), without changing the pressor responses to angiotensin II into the RVLM.”
Importance of angiotensinergic mechanisms for the pressor response to l-glutamate into the rostral ventrolateral medulla“In addition, the pressor and sympathoexcitatory responses evoked by L-Glu were attenuated by losartan in a dose-dependent manner.”
“The increases of MAP evoked by L-Glu (53 +/- 6 mmHg in SHR and 39 +/- 3 mmHg in WKY) were suppressed to 5 +/- 3 mmHg (P < 0.01) and 4 +/- 2 mmHg (P < 0.01), respectively, in the presence of 10 nmol of losartan.”
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