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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Loperamide
supplement:
Senna
Research Papers that Mention the Interaction
“Distal colonic pH fell with wheat bran and senna and tended to increase with loperamide.”
“Faecal SCFA concentrations, including butyrate, increased with senna and fell with loperamide.”
Increasing butyrate concentration in the distal colon by accelerating intestinal transit“Indometacin, loperamide , and calcium-channel antagonists (verapamil, nifedipine) partially antagonized the effect of intracecal sennosides on LIT and delayed, but did not suppress, appearance of soft feces.”
Effect of sennosides and related compounds on intestinal transit in the rat.
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