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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Loperamide
supplement:
Quercetin
Research Papers that Mention the Interaction
“ LOP N-demethylation was significantly inhibited when coincubated with quercetin (a CYP2C8 inhibitor) and ketoconazole (a CYP3A4 inhibitor) by 40 and 90%, respectively, but other chemical inhibitors tested showed weak or no significant inhibition.”
Identification of cytochrome P450 isoforms involved in the metabolism of loperamide in human liver microsomes
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