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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Loperamide
supplement:
Calcium Supplement
Research Papers that Mention the Interaction
“Electrolyte loss was significantly diminished with loperamide : Daily sodium and chloride outputs significantly decreased; daily calcium , phosphate and potassium outputs slightly decreased.”
Effect of loperamide on fecal output and composition in well-established ileostomy and ileorectal anastomosis“ Loperamide actually appeared to enhance influx of calcium via the activated CRAC channels.”
“ Loperamide also inhibited spontaneous and high K+ precontractions as well as shifted the Ca++ CRCs to the right.”
Antidiarrhoeal and spasmolytic activities of the methanolic crude extract of Alstonia scholaris L. are mediated through calcium channel blockade“ Loperamide also inhibited spontaneous and high K+‐induced contractions and shifted the Ca++ CRCs to the right.”
“The inhibitory action of loperamide on the potassium-induced contraction could partly be counteracted by elevation of the calcium concentration in the medium.”
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