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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Linolenic Acid and Ghrelin

supplement:

Linolenic Acid

drug:

Ghrelin

Research Papers that Mention the Interaction

Addition of octanoic acid or α-linolenic acid to MGN3-1 cells increased and decreased octanoyl ghrelin levels, respectively.
PloS one  •  2012  |  View Paper
However, stearic acid, oleic acid, linoleic acid, and α-linolenic acid significantly suppressed octanoylated ghrelin production, with the effect of oleic acid being the strongest.
Journal of oleo science  •  2015  |  View Paper
Addition of GW-9508 (a GPR120 chemical agonist) and α-linolenic acid (a natural ligand for GPR120) inhibited the secretion of ghrelin by ∼50 and 70%, respectively.
American journal of physiology. Endocrinology and metabolism  •  2014  |  View Paper