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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Linoleic Acid
drug:
Phospholipids
Research Papers that Mention the Interaction
“The n-3 LCPUFA content of plasma phospholipids was significantly increased after the low LA diet compared to baseline (6.22% vs. 5.53%, P<0.001).”
A low omega-6 polyunsaturated fatty acid (n-6 PUFA) diet increases omega-3 (n-3) long chain PUFA status in plasma phospholipids in humans.“The fatty acid composition of biliary phospholipids showed a significant enrichment of linoleic acid by both lipid infusions.”
“There were significant increases in relative concentrations of linoleic acid in plasma phospholipids when on the high P/S ratio diet.”
“The linoleic acid content was significantly decreased both in the total fraction of the phospholipids and in the isolated phosphatidylcholine.”
“ Phospholipids and cholesterol esters obtained from animals fed prenatally a linoleic acid rich diet stimulated the PGI2 formation.”
“In addition, the percentage of linoleic acid was lower in boxers' erythrocyte PL than in the control group (P <0.05).”
“In conclusion, high LA intakes decrease plasma phospholipid EPA and increase the ARA:EPA ratio, but do not favor higher ARA.”
“Exogenous exposure to EPA or LA increased its content in membrane phospholipids while concurrently decreasing LA or EPA content, respectively, in a dose-dependent manner.”
“ Linolic and ar achidonic acid content in serum phospholipids decreased significantly (p<0.01 andcl p<0.001, respectively).”
“A significant and dose-dependent 25-45% reduction in linoleic acid (18:2(n-6), LA) was found in serum phospholipids , while a smaller decrease was observed in total serum lipids.”
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